Chronic Sinusitis


BiRch Chronic Rhinosinusitis without Nasal Polyps

Study Title

A Phase 2b, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study of the Efficacy and Safety of Brensocatib in Participants with Chronic Rhinosinusitis Without Nasal Polyps – The BiRCh Study

Study duration

28 weeks


Up to 9 Visits

Main entry criteria
  • 18 – 75 years of age
  • Diagnosis of chronic sinusitis without nasal polyps for at least 12 weeks
  • Have had surgery for chronic sinusitis or been treated in the last 12 months with antibiotics or oral steroids
  • Currently troubled with symptoms of sinusitis

There are additional eligibility requirements to enrol in this study. Our Study Doctor will review the study requirements and discuss your eligibility with you either over the telephone or at your first clinic visit.

  • Nasal endoscopies
  • Smell tests
  • Blood pressure and pulse measurements
  • Electronic Diary Questionnaires
  • ECGs
  • Blood and urine tests
  • Sinus CT scan

You will receive all study-related procedures, medications, and laboratory services at no cost. In addition, you will be reimbursed $70 per visit for your time and travel.