Chronic Sinusitis
Current Chronic Sinusitis Studies
OTICARA Study
Study Title
The effect of intra-sinus application of Betamethasone Dipropionate nasal cream on patients with Chronic Rhinosinusitis post functional endoscopic sinus surgery (FESS)
Study Duration
- Up to 10 weeks
Number of clinic visits
- Up to 4
Number of phone calls
- Up to 3
Main Entry Criteria
- 18 to 80 years of age
- Confirmed diagnosis of CRS by an ENT
- Having undergone functional endoscopic sinus surgery (FESS) at least 6 months prior to enrolment.
There are additional eligibility requirements to enrol in this study. Our Study Doctor will review the study requirements and discuss your eligibility with you either over the telephone or at your first clinic visit.
Assessments
- Nasal endoscope
- Blood pressure and pulse
- Questionnaires
- Intraocular Pressure (IOP)
- Blood and urine tests
- UPSIT (University of Pennsylvania Smell Identification Test)
You will receive all study-related procedures, medications, and laboratory services at no cost. In addition, you will be reimbursed $100 per visit for your time and travel.
Study Status
- Currently recruiting – Osborne Park
Ceren 2
Study Title
A randomized, double-blind, placebo-controlled, parallel-group, 52 week Phase 3 trial to investigate the efficacy, safety, and tolerability of itepekimab in adult participants with inadequately controlled chronic rhinosinusitis with nasal polyps
Study Duration
- Up to 76 weeks
Number of clinic visits
- Up to 9
Number of phone calls
- Up to 20
Main Entry Criteria
- Over 18 years of age
- History of chronic rhinosinusitis with nasal polyp(s) for at least 1 year
- Prior sinonasal surgery for nasal polyps
- Loss of smell or rhinorrhea (anterior/posterior)
There are additional eligibility requirements to enrol in this study. Our Study Doctor will review the study requirements and discuss your eligibility with you either over the telephone or at your first clinic visit.
Assessments
- ECG
- Blood pressure and pulse
- Blood and urine tests
- Nasal endoscopy
- CT Scan
- Questionnaires
- Spirometry for patients with Asthma
You will receive all study-related procedures, medications, and laboratory services at no cost. In addition, you will be reimbursed per visit for your time and travel.
Study Status
- Recruitment opening soon – Spearwood
BIRCH
Study Title
A Phase 2b, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study of the Efficacy and Safety of Brensocatib in Participants with Chronic Rhinosinusitis Without Nasal Polyps – The BiRCh Study
Study Duration
- 28 weeks
Number of clinic visits
- Up to 9 Visits
Main Entry Criteria
- Over 18 years of age
- Diagnosis of chronic sinusitis without nasal polyps for at least 12 weeks
- Have had surgery for chronic sinusitis or been treated in the last 12 months with antibiotics or oral steroids
- Currently troubled with symptoms of sinusitis
There are additional eligibility requirements to enrol in this study. Our Study Doctor will review the study requirements and discuss your eligibility with you either over the telephone or at your first clinic visit.
Assessments
- Nasal endoscopies
- Smell tests
- Blood pressure and pulse measurements
- Electronic Diary Questionnaires
- ECGs
- Blood and urine tests
- Sinus CT scan
You will receive all study-related procedures, medications, and laboratory services at no cost. In addition, you will be reimbursed $70 per visit for your time and travel.
Study Status
- Currently recruiting – Spearwood